Here is my five point guidance of "nothing"
1. Nothing happens without work, it is absolutely important to work in order to better our situations. Some people go as far as defining luck as being good preparations meeting good opportunity.
2. Nothing happens before it's time. This is a complex tautology. Far for advising complacency, a careful analysis will see that this tautology stresses to us to push for the changes we want (as we do not know the appointed time for these changes to happen), but to not despair if the changes do not happen at the timeframe we want these changes to happen.
3. If you frame your context right, nothing will be impossible. The question is, are you framing your context, aligning your talents, focus and resources right?
4. Nothing ethical is beneath the humble seeker. If an opportunity presents itself, but it is not up to the intellectual challenges you want, the job you went to school to do, your social status, etc, but it is legal, ethical and can support you at least for some time while you are aligning your other targets, take it. Albert Einstein was once working as a paltry patent officer in what must have been the lowest level of civil service ranks in Bern, Switzerland. That was just his day job, at night he wrote serious physics papers and corresponded with world famous physicists promoting his ideas. Today, he is a legend. That paltry desk job enabled him to support himself and his family and do his physics without worrying about rent money.
5. Nothing can stop an enterprising smart person. If something is in your way, take that as an opportunity to overcome. Alexander The Great used to cry to his father, that the father, Phillip of Macedonia, was fighting too many wars, killing too many enemies. Alexander was afraid that by the time he grew up, there would be no more enemies to fight and no more lands to conquer. He must have thought "what a boring and inglorious life that would be". Let no crisis go to waste.
Now I feel like I am one of those motivational speakers.