Dawa ya herpes simplex virus

C

chigwiye

JF-Expert Member
Oct 28, 2010
352
59
Wapendwa ktk mwenyezi,nawasalimu.
Nawasihi tusichoke kusaidiana.naomba msaada kwa anayejua dawa ya herpes simplex virus atusaidie,hata kama ni ya jadi.poleni kwa usumbufu
 
Kwa herpes simplex huwa ni self limiting, inasumbua tu ikipata secondary bacteria infection. Kwa hiyo inategemea zipo sehemu gani. For me most of my patients huwa nawaandikia Acyclovir cream anatumia mara tatu kwa siku. Kama pana bacteria infection most common ni S. Aureus namwandikia na cloxacillin na anti pain. Amitryptline has no role in this case. I wish u best luck
 
Barca said:
Kwa herpes simplex huwa ni self limiting, inasumbua tu ikipata secondary bacteria infection. Kwa hiyo inategemea zipo sehemu gani. For me most of my patients huwa nawaandikia Acyclovir cream anatumia mara tatu kwa siku. Kama pana bacteria infection most common ni S. Aureus namwandikia na cloxacillin na anti pain. Amitryptline has no role in this case. I wish u best luck
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Mkuu, mbona nasikia herpes huwa haziponi, au mimi nina info za zamani?
 
Ni sawa kabisa HSV inaweza kutubiwa na high dose ya intravenous Acyclovir ila hapa kwetu sijaziona hivyo ni vidonge tu hasa kwa dose kubwa kama 800mg kila baada ya saa 6 kwa wiki 2 na pia usisahau kutibu bacteria infection kwenye ngoZi kwa antibiotic kama Flucamox caps na Amitryptiline pia ni nzuri kwa neuralgic pain hizi umeze usiku tu.
 
Chloroquine said:
Ni sawa kabisa HSV inaweza kutubiwa na high dose ya intravenous Acyclovir ila hapa kwetu sijaziona hivyo ni vidonge tu hasa kwa dose kubwa kama 800mg kila baada ya saa 6 kwa wiki 2 na pia usisahau kutibu bacteria infection kwenye ngoZi kwa antibiotic kama Flucamox caps na Amitryptiline pia ni nzuri kwa neuralgic pain hizi umeze usiku tu.
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Ni kweli kabisa combination hiyo nimeikubali zaidi.
 
Amitryptiline 25mg hizi ni Tricyclic Antidepressant zinatibu mambo mengi ikiwemo neuropathic pain, depression japokuwa zipo nzuri zaidi kwa hili.
 
Hapo ndipo tunapokua tunagombana nanyi kila siku. Why umpe mtu amytriptillin? Herpes simplex bado ambayo pathophysiology inamanifest with vesicles hakuna sababu ya kumpa dawa ya neurological pain, kumbuka unampa mtu dawa zinaenda kua metabolised na liver excreted by the kidney na Herpes in ugonjwa ambao atakaa nao mpaka anakufa being recurrent as the ganglion serves as reservoir sasa we kila anakuja na vesicles tu tena majority of the patients zinakua itchy and not painfull unampachika amytriptillin tu without even a reason to, hebu mue mnaangalia na genuine reasons za polytherapy co mtu ukijiskia tu unapanga madawa. Antibiotics i totally agree with that hilo halina doubt even though lazma uangalie na severity of the pathology pia.
 
UmkhontoweSizwe said:
Mkuu, mbona nasikia herpes huwa haziponi, au mimi nina info za zamani?
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Herpes simplex (Greek: ἕρπης herpēs, "creeping" or "latent") is a viral disease from the herpesviridae family caused by both Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2). Infection with the herpes virus is categorized into one of several distinct disorders based on the site of infection. Oral herpes, the visible symptoms of which are colloquially called cold sores or fever blisters, is an infection of the face or mouth. Oral herpes is the most common form of infection. Genital herpes, known simply as herpes, is the second most common form of herpes. Other disorders such as herpetic whitlow, herpes gladiatorum, ocular herpes, cerebral herpes infection encephalitis, Mollaret's meningitis, neonatal herpes, and possibly Bell's palsy are all caused by herpes simplex viruses.
Herpes viruses cycle between periods of active disease—presenting as blisters containing infectious virus particles—that last 2–21 days, followed by a remission period. Genital herpes, however, is often asymptomatic, though viral shedding may still occur. After initial infection, the viruses are transported along sensory nerves to the sensory nerve cell bodies, where they become latent and reside lifelong. Causes of recurrence are uncertain, though some potential triggers have been identified, including immunosuppressant drugs. The previously latent virus then multiplies new virus particles in the nerve cell and these are transported along the axon of each neuron to the nerve terminals in the skin, where they are released. Over time, episodes of active disease reduce in frequency and severity.
Herpes simplex is most easily transmitted by direct contact with a lesion or the body fluid of an infected individual. Transmission may also occur through skin-to-skin contact during periods of asymptomatic shedding. Barrier protection methods are the most reliable method of preventing transmission of herpes, but they merely reduce rather than eliminate risk. Oral herpes is easily diagnosed if the patient presents with visible sores or ulcers. Early stages of orofacial herpes and genital herpes are harder to diagnose; laboratory testing is usually required.
A cure for herpes has not yet been developed. Once infected, the virus remains in the body for life. Recurrent infections (outbreaks) may occur from time to time, especially in times of immune impairment such as HIV and cancer-related immune suppression.[SUP][1][/SUP] However, after several years, outbreaks become less severe and more sporadic, and some people will become perpetually asymptomatic and will no longer experience outbreaks, though they may still be contagious to others. Treatments with antivirals can reduce viral shedding and alleviate the severity of symptomatic episodes. It should not be confused with conditions caused by other viruses in the herpesviridae family such as herpes zoster, which is caused by varicella zoster virus. The differential diagnosis includes hand, foot and mouth disease due to similar lesions on the skin.


[h=2]Classification[/h] Herpes simplex is divided into two types: HSV type 1 and HSV type 2. HSV1 causes primarily mouth, throat, face, eye, and central nervous system infections, whereas HSV2 causes primarily anogenital infections. However, each may cause infections in all areas.[SUP][2][/SUP]
[h=2]Signs and symptoms[/h] HSV infection causes several distinct medical disorders. Common infection of the skin or mucosa may affect the face and mouth (orofacial herpes), genitalia (genital herpes), or hands (herpetic whitlow). More serious disorders occur when the virus infects and damages the eye (herpes keratitis), or invades the central nervous system, damaging the brain (herpes encephalitis). People with immature or suppressed immune systems, such as newborns, transplant recipients, or people with AIDS are prone to severe complications from HSV infections. HSV infection has also been associated with cognitive deficits of bipolar disorder,[SUP][3][/SUP] and Alzheimer's disease, although this is often dependent on the genetics of the infected person.
In all cases HSV is never removed from the body by the immune system. Following a primary infection, the virus enters the nerves at the site of primary infection, migrates to the cell body of the neuron, and becomes latent in the ganglion.[SUP][4][/SUP] As a result of primary infection, the body produces antibodies to the particular type of HSV involved, preventing a subsequent infection of that type at a different site. In HSV-1 infected individuals, seroconversion after an oral infection will prevent additional HSV-1 infections such as whitlow, genital herpes, and herpes of the eye. Prior HSV-1 seroconversion seems to reduce the symptoms of a later HSV-2 infection, although HSV-2 can still be contracted.
Many people infected with HSV-2 display no physical symptoms—individuals with no symptoms are described as asymptomatic or as having subclinical herpes.[SUP][5][/SUP]
ConditionDescriptionIllustration
Herpetic gingivostomatitisHerpetic gingivostomatitis is often the initial presentation during the first herpes infection. It is of greater severity than herpes labialis, which is often the subsequent presentations.

Herpes labialisInfection occurs when the virus comes into contact with oral mucosa or abraded skin.

Herpes genitalisWhen symptomatic, the typical manifestation of a primary HSV-1 or HSV-2 genital infection is clusters of inflamed papules and vesicles on the outer surface of the genitals resembling cold sores.

Herpetic whitlow and Herpes gladiatorumHerpes whitlow is a painful infection that typically affects the fingers or thumbs. On occasion, infection occurs on the toes or on the nail cuticle. Individuals that participate in contact sports such as wrestling, rugby, and soccer sometimes acquire a condition caused by HSV-1 known as herpes gladiatorum, scrumpox, wrestler’s herpes, or mat herpes, which presents as skin ulceration on the face, ears, and neck. Symptoms include fever, headache, sore throat and swollen glands. It occasionally affects the eyes or eyelids.

[h=2]Prevention[/h]
Barrier protection, such as a condom, can reduce the risk of herpes transmission.


As with almost all sexually transmitted infections, women are more susceptible to acquiring genital HSV-2 than men.[SUP][28][/SUP] On an annual basis, without the use of antivirals or condoms, the transmission risk of HSV-2 from infected male to female is approximately 8–11%.[SUP][23][/SUP][SUP][29][/SUP] This is believed to be due to the increased exposure of mucosal tissue to potential infection sites. Transmission risk from infected female to male is approximately 4–5% annually.[SUP][29][/SUP] Suppressive antiviral therapy reduces these risks by 50%.[SUP][30][/SUP] Antivirals also help prevent the development of symptomatic HSV in infection scenarios—meaning the infected partner will be seropositive but symptom free—by about 50%. Condom use also reduces the transmission risk significantly.[SUP][31][/SUP][SUP][32][/SUP] Condom use is much more effective at preventing male to female transmission than vice-versa.[SUP][31][/SUP] The effects of combining antiviral and condom use is roughly additive, thus resulting in approximately a 75% combined reduction in annual transmission risk.[SUP][citation needed][/SUP] These figures reflect experiences with subjects having frequently recurring genital herpes (>6 recurrences per year). Subjects with low recurrence rates and those with no clinical manifestations were excluded from these studies.[SUP][citation needed][/SUP] Previous HSV-1 infection appears to reduce the risk for acquisition of HSV-2 infection among women by a factor of 3.[SUP][33][/SUP]
However, asymptomatic carriers of the HSV-2 virus are still contagious. In many infections, the first symptom a person will have of their own infection is the horizontal transmission to a sexual partner or the vertical transmission of neonatal herpes to a newborn at term. Since most asymptomatic individuals are unaware of their infection, they are considered at high risk for spreading HSV.[SUP][citation needed][/SUP]
In October 2011, it was reported that the anti-HIV drug tenofovir, when used topically in a microbicidal vaginal gel, reduced herpes virus sexual transmission by 51%.[SUP][34][/SUP]
[h=3]Barrier methods[/h] Condoms offer moderate protection against HSV-2 in both men and women, with consistent condom users having a 30% lower risk of HSV-2 acquisition compared with those that never use condoms.[SUP][35][/SUP] A female condom can provide greater protection than the male condom, as it covers the labia.[SUP][36][/SUP] The virus cannot pass through a synthetic condom, but a male condom's effectiveness is limited[SUP][37][/SUP] because herpes ulcers may appear on areas not covered by the male condom. Neither type of condom prevents contact with the scrotum, anus, buttocks, or upper thighs, areas that may come in contact with ulcers or genital secretions during sexual activity. Protection against herpes simplex depends on the site of the ulcer; therefore if ulcers appear on areas not covered by condoms, abstaining from sexual activity until the ulcers are fully healed is one way to limit risk of transmission.[SUP][38][/SUP] The risk is not eliminated, however, as viral shedding capable of transmitting infection may still occur while the infected partner is asymptomatic.[SUP][39][/SUP] The use of condoms or dental dams also limits the transmission of herpes from the genitals of one partner to the mouth of the other (or vice versa) during oral sex. When one partner has a herpes simplex infection and the other does not, the use of antiviral medication, such as valaciclovir, in conjunction with a condom further decreases the chances of transmission to the uninfected partner.[SUP][4][/SUP] Topical microbicides that contain chemicals that directly inactivate the virus and block viral entry are being investigated.[SUP][4][/SUP]
[h=3]Antivirals[/h] Antivirals may reduce asymptomatic shedding; it is believed asymptomatic genital HSV-2 viral shedding occurs on 20% of days per year in patients not undergoing antiviral treatment, versus 10% of days while on antiviral therapy.[SUP][19][/SUP]
[h=3]Pregnancy[/h] The risk of transmission from mother to baby is highest if the mother becomes infected at around the time of delivery (30% to 60%),[SUP][40][/SUP][SUP][41][/SUP] since insufficient time will have occurred for the generation and transfer of protective maternal antibodies before the birth of the child. In contrast, the risk falls to 3% if it is a recurrent infection,[SUP][42][/SUP] and is 1–3% is the woman seropositive for both HSV-1 and HSV-2,[SUP][42][/SUP][SUP][43][/SUP] and is less than 1% if there are no visible lesions.[SUP][42][/SUP] Women seropositive for only one type of HSV are only half as likely to transmit HSV as infected seronegative mothers. To prevent neonatal infections, seronegative women are recommended to avoid unprotected oral-genital contact with an HSV-1 seropositive partner and conventional sex with a partner having a genital infection during the last trimester of pregnancy. Mothers infected with HSV are advised to avoid procedures that would cause trauma to the infant during birth (e.g. fetal scalp electrodes, forceps, and vacuum extractors) and, should lesions be present, to elect caesarean section to reduce exposure of the child to infected secretions in the birth canal.[SUP][4][/SUP] The use of antiviral treatments, such as acyclovir, given from the 36th week of pregnancy, limits HSV recurrence and shedding during childbirth, thereby reducing the need for caesarean section.[SUP][4][/SUP]
Acyclovir is the recommended antiviral for herpes suppressive therapy during the last months of pregnancy. The use of valaciclovir and famciclovir, while potentially improving compliance have less well determined safety in pregnancy.
[h=2]Treatment[/h] There is no method to eradicate herpes virus from the body, but antiviral medications can reduce the frequency, duration, and severity of outbreaks. Analgesics such as ibuprofen and acetaminophen can reduce pain and fever. Topical anesthetic treatments such as prilocaine, lidocaine, benzocaine or tetracaine can also relieve itching and pain.[SUP][44][/SUP][SUP][45][/SUP][SUP][46][/SUP]
[h=3]Antiviral[/h]
The antiviral medication acyclovir


There are several antivirals that are effective for treating herpes including: aciclovir (acyclovir), valaciclovir (valacyclovir), famciclovir, and penciclovir. Aciclovir was the first discovered and is now available in generic.[SUP][47][/SUP] Valacyclovir is also available as a generic.[SUP][48][/SUP]
Evidence supports the use of aciclovir and valaciclovir in the treatment of herpes labialis[SUP][49][/SUP] as well as herpes infections in people with cancer.[SUP][50][/SUP] The evidence to support the use of acyclovir in primary herpetic gingivostomatitis is less strong.[SUP][51][/SUP]
[h=3]Topical[/h] A number of topical antivirals are effective for herpes labialis including acyclovir, penciclovir, and docosanol.[SUP][49][/SUP][SUP][52][/SUP]
[h=3]Alternative medicine[/h] Certain dietary supplements and alternative remedies are claimed to be beneficial in the treatment of herpes.[SUP][53][/SUP] There is however insufficient evidence to support use of many of these compounds including echinacea, eleuthero, L-lysine, zinc, monolaurin bee products and aloe vera.[SUP][54][/SUP] While there are a number of small studies showing possible benefit from monolaurin, L-lysine, aspirin, lemon balm, topical zinc or licorice root cream in treatment, these are preliminary studies that have not been confirmed by higher quality randomized controlled studies.[SUP][55][/SUP]
[h=2]Prognosis[/h] Following active infection, herpes viruses establish a latent infection in sensory and autonomic ganglia of the nervous system. The double-stranded DNA of the virus is incorporated into the cell physiology by infection of the nucleus of a nerve's cell body. HSV latency is static—no virus is produced—and is controlled by a number of viral genes, including Latency Associated Transcript (LAT).[SUP][56][/SUP]
Many HSV-infected people experience recurrence within the first year of infection.[SUP][4][/SUP] Prodrome precedes development of lesions. Prodromal symptoms include tingling (paresthesia), itching, and pain where lumbosacral nerves innervate the skin. Prodrome may occur as long as several days or as short as a few hours before lesions develop. Beginning antiviral treatment when prodrome is experienced can reduce the appearance and duration of lesions in some individuals. During recurrence, fewer lesions are likely to develop, lesions are less painful and heal faster (within 5–10 days without antiviral treatment) than those occurring during the primary infection.[SUP][4][/SUP] Subsequent outbreaks tend to be periodic or episodic, occurring on average four to five times a year when not using antiviral therapy.
The causes of reactivation are uncertain, but several potential triggers have been documented. A recent study (2009) showed that the protein VP16 plays a key role in reactivation of the dormant virus.[SUP][57][/SUP] Changes in the immune system during menstruation may play a role in HSV-1 reactivation.[SUP][58][/SUP][SUP][59][/SUP] Concurrent infections, such as viral upper respiratory tract infection or other febrile diseases, can cause outbreaks. Reactivation due to infection is the likely source of the historic terms cold sore and fever blister.
Other identified triggers include: local injury to the face, lips, eyes, or mouth, trauma, surgery, radiotherapy, and exposure to wind, ultraviolet light, or sunlight.[SUP][60][/SUP][SUP][61][/SUP][SUP][62][/SUP][SUP][63][/SUP][SUP][64][/SUP]
The frequency and severity of recurrent outbreaks vary greatly between people. Some individuals' outbreaks can be quite debilitating with large, painful lesions persisting for several weeks, while others will experience only minor itching or burning for a few days. There is some evidence that genetics plays a role in the frequency of cold sore outbreaks. An area of human chromosome 21 that includes 6 genes has been linked to frequent oral herpes outbreaks. An immunity to the virus is built over time. Most infected individuals will experience fewer outbreaks and outbreak symptoms will often become less severe. After several years, some people will become perpetually asymptomatic and will no longer experience outbreaks, though they may still be contagious to others. Immuno-compromised individuals may experience episodes that are longer, more frequent, and more severe. Antiviral medication has been proven to shorten the frequency and duration of outbreaks.[SUP][65][/SUP] Outbreaks may occur at the original site of the infection or in proximity to nerve endings that reach out from the infected ganglia. In the case of a genital infection, sores can appear at the original site of infection or near the base of the spine, the buttocks, or the back of the thighs. HSV-2 infected individuals are at higher risk for acquiring HIV when practicing unprotected sex with HIV-positive persons, in particular during an outbreak with active lesions.[SUP][66][/SUP]
 
Picture of Herpes Simplex Virus Type 1



stds-s7-photo-of-herpes-simplex-virus-type-1.jpg



​Herpes simplex type 1: A herpes virus that causes cold sores and feverblisters in and around the mouth.:In rare cases, as when someone's immune system is severely compromised, this virus can cause infection of the brain (encephalitis).
Herpes simplex type 1 is also known as human herpesvirus 1 (HHV-1).

​




8. Picture of Herpes Simplex Virus Type 2



stds-s8-photo-of-herpes-simplex-virus-type-2.jpg

Herpes simplex type 2: A herpes virus that causes genital herpes, which is characterized by sores in the genital area. Genital herpes is a sexually transmitted disease (STD).
This virus, like herpes simplex type 1, can also cause infection of the brain (encephalitis) if the immune system is severely defective or compromised. The treatment of infection with herpes simplex type 2 is by topical or oral anti-viral medication.
Herpes simplex type 2 is also known as human herpesvirus 2 (HHV-2).​
 
Mkuu.@chigwiye Dawa ya Herpes Simple Virus Mimi ninakupa Dawa ya Tiba Mbadala jaribu hii Nunua kitunguu swaumu Kimoja kizima.Menya

chote kama vile uandaavyo kwa ajili ya kupikia.Twanga ama saga,vikisha sagika changanya na maji ya uvuguvugu kidogo

kipimo cha kijiko cha chai ili vilainike.Chota msagiko wote wa vitunguu na uvimeze.

Tahadhari,jitahidi uwe na mfuko ama sehemu ya maliwatoni maana kama hauna tumbo zuri unaweza tapika.(Mara chache

sana hutokea kutapika) Ukishakaa kama dk 15 hali yako itarudi kawaida. Jaribu kutumia kila siku Asubuhi kabla ya kula

kitu tumia hii dawa mpaka hapo utakapo pona maradhi yako kisha uje hapa unipe Feedback.


Na Dawa ingine ya Herpes Simple Virus Jaribu kutumia Dawa hii Malengelenge ya Neva katika Ngozi Utajipaka – sehemu ya malengelenge – mafuta ya Habbat-Sawdaa mara tatu kila siku mpaka iondoke


Nigella_Sativa_Oil.jpg

Nigella Sativa Oil mafuta ya Habbat-Sawdaa

Kama upo Mjini Dares-Salaam nenda katika Maduka ya Super Market makubwa kaulizie hayo Mafuta utapata inshallah.
 
chigwiye said:
Wapendwa ktk mwenyezi,nawasalimu.
Nawasihi tusichoke kusaidiana.naomba msaada kwa anayejua dawa ya herpes simplex virus atusaidie,hata kama ni ya jadi.poleni kwa usumbufu
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Kwanza punguza kunywa pombe kama unatumia au soda soda pili jaribu kutumi vitamin b complex pamoja nakula vitungu thaum mara kwa mara
 
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