Fasting may be the best way to combat cancer

LONDON: Fasting for short periods could help combat cancer and boost effectiveness of its treatments, a new study has claimed.
Researchers at University of Southern California found that fasting slowed the growth and spread of tumours and cured some

cancers when it was combined with chemotherapy . It's hoped that the findings will lead to the development of more effective treatment plans and further research is now under way, they said.

In experiments on mice, they found tumour cells responded differently to the stress of fasting compared to normal cells. Instead of entering a dormant state similar to hibernation, the cells kept growing and dividing, in the end destroying themselves, they said.

"The cell is, in fact, committing cellular suicide," lead study author Valter Longo was quoted as saying by the Daily Mail. "What we are seeing is that the cancer cell tries to compensate for the lack of all these things missing in the blood after fasting. It may be trying to replace them, but it cannot."

For the study, published in the journal Science Translational Medicine, Longo and his team looked at the impact fasting had on breast, urinary tract and ovarian cancers in mice. Fasting without chemotherapy was shown to slow the growth of breast cancer, melanoma skin cancer, glioma brain cancer and neuroblastoma - a cancer that forms in the nerve tissue.

In every case, combining fasting with chemotherapy made the cancer treatment more effective. But none of the mice survived if they were treated with chemotherapy alone.

According to the researchers, they are already examining the effects of fasting on human patients , but only a clinical trial lasting several years will confirm if human cancer patients really can benefit from calorie restriction.

Source. Fasting may be the best way to combat cancer - Times Of India

Kufunga kunaweza kusaidia kutibu maradhi ya Saratani haya tena ndugu zangu wale wenye Maradhi ya Saratani muwe munafunga Haijali wewe ni Muislam wala Mkristo Kufunga kunasaida kutibu Maradhi ya Kansa kwa mtu yoyote yule mwenye imani ya kufunga Fungeni mupone Maradhi ya Kansa.

Fasting 'could help combat cancer and boost effectiveness of treatments'

• Fasting slowed growth and spread of tumours
• Cured some cancers if combined with chemotherapy
• Human trials now under way

Going without food for short periods may help to combat cancer and boost the effectiveness of treatments, say scientists.
A study found fasting slowed the growth and spread of tumours and cured some cancers when it was combined with chemotherapy.
It is hoped that the discovery will prompt the development of more effective treatment plans and further research is now under way.



Fasting may help to combat cancer and boost the effectiveness of treatment


The latest investigation, published in the journal Science Translational Medicine, found that tumour cells responded differently to the stress of fasting compared to normal cells.
Instead of entering a dormant state similar to hibernation, the cells kept growing and dividing, in the end destroying themselves.


Lead researcher Professor Valter Longo, from the University of Southern California said: 'The cell is, in fact, committing cellular suicide.

'What we're seeing is that the cancer cell tries to compensate for the lack of all these things missing in the blood after fasting. It may be trying to replace them, but it can't.'
Professor Longo and his team looked at the impact fasting had on breast, urinary tract and ovarian cancers in mice.
Fasting without chemotherapy was shown to slow the growth of breast cancer, melanoma skin cancer, glioma brain cancer and neuroblastoma - a cancer that forms in the nerve tissue.


Scientists found tumour cells responded differently to the stress of fasting compared to normal cells

In every case, combining fasting with chemotherapy made the cancer treatment more effective.
Multiple cycles of fasting combined with chemotherapy cured 20 per cent of those with a highly aggressive form of cancer while 40 per cent with a limited spread of the same cancer were cured.

None of the mice survived if they were treated with chemotherapy alone.

Researchers are already investigating the effects of fasting on human patients, but only a clinical trial lasting several years will confirm if human cancer patients really can benefit from calorie restriction.

However they highlight that fasting could be dangerous for patients who have already lost a lot of weight or are affected by other risk factors, such as diabetes.

Results of a preliminary clinical trial will be presented at an annual meeting of the American Society of Cancer Oncologists (Asco) in Chicago this June.

Prof Longo points out that the study only tests if patients could tolerate short fasts of two days before and one day after chemotherapy.

'We don't know whether in humans it's effective,' he said.

'It should be off-limits to patients, but a patient should be able to go to their oncologist and say, 'what about fasting with chemotherapy?' or without if chemotherapy was not recommended or considered.'

Previous research led by Prof Longo showed that fasting protected normal cells from the effects of chemotherapy but it did not look at cancer cells.

It is now though fasting may be one way to make tumour cells weaker and more vulnerable.

Prof Longo added: 'A way to beat cancer cells may not be to try to find drugs that kill them specifically but to confuse them by generating extreme environments, such as fasting, that only normal cells can quickly respond to.'
source. http://www.dailymail.co.uk/health/article-2098363/Fasting-help-combat-cancer-boost-effectiveness-treatments.html#axzz2JgxgMAM0

MziziMkavu wengi English not present today sir.
Unaonaje ukiingia hata gugo transeleta media ili tukuelewe na kuufaidi uzi huu?

Habari hii imeripotiwa toka London: Kufunga kwa muda mfupi inaweza kusaidia kupambana na saratani na kuongeza ufanisi wa matibabu yake, utafiti mpya umedai.

Watafiti katika Chuo Kikuu cha Southern California wamesema kuwa kupatikana kwamba kufunga na ukuaji na ueneaji wa uvimbe na kutibiwa baadhi ya


saratani wakati ilikuwa pamoja na kidini. Ni matumaini ya Serikali kwamba matokeo itasababisha maendeleo ya mipango ya ufanisi zaidi wa matibabu na utafiti zaidi sasa chini ya njia, walisema.

Katika majaribio juu ya panya, walikuta Uvimbe wa seli majibu tofauti na msongo wa kufunga ikilinganishwa na seli za kawaida. Badala ya kuingia hali dormant sawa na hibernation, Seli inaendelea kukua na kugawa, katika mwisho kuharibu wenyewe, walisema.


"Kiini ni, kwa kweli, wanajiua seli," utafiti kuongoza mwandishi Longo Valter alinukuliwa akisema na Daily Mail. "Tunachokiona ni kwamba kiini kansa inajaribu fidia kwa ukosefu wa mambo haya yote kukosa katika damu baada ya kufunga Inaweza kujaribu kuchukua nafasi yao., Lakini hawawezi."


Kwa ajili ya utafiti, iliyochapishwa katika jarida Sayansi Translational Madawa, Longo na timu yake inaonekana katika kufunga kuna athari iliyokuwa juu ya njia ya matiti, mkojo na saratani ya ovari katika panya. Kufunga bila kidini alionyeshwa ili kupunguza ukuaji wa kansa ya matiti, melanoma kansa ya ngozi, kansa ya ubongo na glioma neuroblastoma - kansa kwamba fomu katika tishu za neva.


Kwa kila hali, kuchanganya kufunga na chemotherapy kulifanya matibabu ya kansa na ufanisi zaidi. Lakini hakuna panya alinusurika kama walikuwa kutibiwa na kidini peke yake.


Kulingana na watafiti, tayari kuchunguza madhara ya kufunga juu ya wagonjwa wa binadamu, lakini tu kesi ya kliniki ya kudumu miaka kadhaa itakuwa kuthibitisha kama binadamu kansa ya wagonjwa kwa kweli wanaweza kunufaika na kizuizi calorie.

Kufunga Kunaweza kusaidia kupambana na saratani na kuongeza ufanisi wa matibabu'




Kufunga kunasaidia taratibu kutibu ukuaji na ueneaji wa Uvimbe

Tiba baadhi ya Saratani ikiwa pamoja na (chemotherapy)

Binadamu majaribio sasa chini ya njia

Kwenda au kukaa bila kula chakula kwa muda mfupi kunaweza kusaidia kupambana na saratani na kuongeza ufanisi wa matibabu, wanasema Wanasayansi.

Utafiti uligundua kufunga taratibu kusaidia kutibu ukuaji na ueneaji wa Uvimbe wa Kansa na kutibiwa baadhi ya Saratani wakati ilikuwa pamoja na kidini.

Ni matumaini kwamba ugunduzi Utasababisha Maendeleo ya Mipango ya Ufanisi Zaidi wa Matibabu na Utafiti Zaidi ni sasa chini ya njia.


Kufunga kunaweza kusaidia kupambana na saratani na kuongeza ufanisi wa matibabu

uchunguzi karibuni, iliyochapishwa katika jarida Sayansi Translational Madawa, iligundua kwamba Uvimbe wa seli ulitoa jibu tofauti na Msongo wa kufunga Ukilinganishwa na Seli za kawaida.

Badala ya kuingia hali dormant sawa na hibernation, Seli Ina endelea kukua na kugawa, katika mwisho kuharibu wenyewe.


Kiongozi Mtafiti Profesa Valter Longo, kutoka Chuo Kikuu cha Southern California nchini Amerika alisema: 'kiini ni, kwa kweli, wanajiua Mkononi.

'Nini sisi ni kuona ni kwamba kiini kansa inajaribu fidia kwa ukosefu wa mambo haya yote kukosa katika damu baada ya

kufunga. Inaweza kuwa na kujaribu kuchukua nafasi yao, lakini siwezi. '

Profesa Longo na timu yake inaonekana katika kufunga kuna athari iliyokuwa ya juu ya njia ya matiti, mkojo na

saratani ya ovari katika panya.

Kufunga bila kidini ilionyeshwa ili kupunguza ukuaji wa kansa ya matiti, melanoma kansa ya ngozi, kansa ya ubongo na

glioma neuroblastoma - kansa kwamba fomu katika tishu za neva.


WanaSayansi kupatikana Uvimbe wa seli ilijibu tofauti na Msongo wa kufunga ikilinganishwa na seli za kawaida

Kwa kila hali, kuchanganya kufunga na chemotherapy Kulifanya Matibabu ya kansa kuwa na ufanisi zaidi.

Multiple mizunguko ya kufunga pamoja na chemotherapy kutibiwa Asilimia 20 ya wale wenye fomu yenye fujo ya kansa

wakati asilimia 40 na kuenea mdogo wa kansa huo wakaponywa.


Hakuna wa panya alinusurika kama walikuwa kutibiwa na kidini peke yake.


Watafiti tayari wameweza kuchunguza madhara ya kufunga juu ya wagonjwa wa binadamu, lakini tu kesi ya kliniki ya

kudumu miaka kadhaa itakuwani ya kuthibitisha kama binadamu kansa ya wagonjwa kwa kweli wanaweza kunufaika na kizuizi calorie.


Hata hivyo wao kuonyesha kwamba kufunga kunaweza kuwa hatari kwa wagonjwa ambao tayari waliopotea mengi ya uzito au walioathirika na mambo mengine hatari, kama vile ugonjwa wa kisukari.


Matokeo ya kesi ya awali ya kliniki itawasilishwa katika mkutano wa mwaka wa jamii ya Marekani ya Oncologists Saratani (Asco) katika Chicago hii Juni.


Prof Longo anasema kuwa utafiti tu vipimo kama wagonjwa wanaweza kuvumilia Mifungo mfupi wa siku mbili kabla na siku moja baada ya kidini.


'Sisi hatujui kama katika binadamu ni nafuu,' alisema.


'Ni lazima kuwa mbali-mipaka kwa wagonjwa, lakini mgonjwa lazima kuwa na uwezo wa kwenda oncologist yao na kusema,' nini kuhusu kufunga na chemotherapy? ' au bila ikiwa kidini ilikuwa haifai au kuchukuliwa. '


Kabla ya utafiti iliyoongozwa na Profesa Longo ilionyesha kwamba kufunga kulindwa seli za kawaida kutokana na athari ya kidini lakini hawakuwa kuangalia seli za saratani.


Ni sasa ingawa kufunga kunaweza kuwa njia moja ya kufanya Uvimbe wa seli kuwa ni dhaifu na mazingira magumu zaidi.


Prof Longo aliongeza: 'njia ya kuwapiga vita seli za saratani inaweza kuwa katika kujaribu kutafuta dawa kuua yao hasa lakini kwa kuwachanganya na kuzalisha mazingira uliokithiri, kama vile kufunga, kwamba tu seli za kawaida wanaweza haraka kujibu.

It is now though fasting may be one way to make tumour cells weaker and more vulnerable.

Prof Longo added: 'A way to beat cancer cells may not be to try to find drugs that kill them specifically but to confuse them by generating extreme environments, such as fasting, that only normal cells can quickly respond to.'

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There is also a need to investigate how extreme environment imposed by fasting affect the general condition of a patient......................it is not only cancerous cells that suffer but the patient too. May be for rats it is easier to ignore the health of a patient and in particular the immunity system whose strength is entirely on calorie intake not its restriction............