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- Feb 11, 2007
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Scientists compared 1,688 diseases to birth dates of 1.7m New Yorkers
Found 55 diseases that correlated with the season of birth
April babies at highest risk of angina, November bronchitis and ADHD
Overall, the Columbia University study indicated people born in May had the lowest disease risk, and those born in October the highest.
'Lifetime disease risk is affected by birth month,' the researchers wrote in in the Journal of American Medical Informatics Association.
'Seasonally dependent early developmental mechanisms may play a role in increasing lifetime risk of disease. '
'This data could help scientists uncover new disease risk factors,' said author Nicholas Tatonetti.
The researchers now plan to replicate their study with data from several other locations in the U.S. and abroad to see how results vary with the change of seasons and environmental factors in those places.
By identifying what's causing disease disparities by birth month, the researchers hope to figure out how they might close the gap.
Earlier research on individual diseases such as ADHD and asthma suggested a connection between birth season and incidence, but no large-scale studies had been undertaken.
Researchers examined New York City medical databases and found 55 diseases that correlated with the season of birth. This data visualization maps the statistical relationship between birth month and disease incidence in the electronic records of 1.7 million New York City patients.
The researchers also uncovered 16 new associations, including nine types of heart disease, the leading cause of death in the United States.
The researchers performed statistical tests to check that the 55 diseases for which they found associations did not arise by chance.
'It's important not to get overly nervous about these results because even though we found significant associations the overall disease risk is not that great,' notes Dr. Tatonetti. 'The risk related to birth month is relatively minor when compared to more influential variables like diet and exercise.'
The new data are consistent with previous research on individual diseases.
For example, the study authors found that asthma risk is greatest for July and October babies.
An earlier Danish study on the disease found that the peak risk was in the months (May and August) when Denmark's sunlight levels are similar to New York's in the July and October period.
For ADHD, the Columbia data suggest that around one in 675 occurrences could relate to being born in New York in November.
This result matches a Swedish study showing peak rates of ADHD in November babies.
The researchers also found a relationship between birth month and nine types of heart disease, with people born in March facing the highest risk for atrial fibrillation, congestive heart failure, and mitral valve disorder.
One in 40 atrial fibrillation cases may relate to seasonal effects for a March birth.
A previous study using Austrian and Danish patient records found that those born in months with higher heart disease rates -March through June -had shorter life spans.
'Faster computers and electronic health records are accelerating the pace of discovery,' said the study's lead author, Mary Regina Boland, a graduate student at Columbia.
'We are working to help doctors solve important clinical problems using this new wealth of data.'
Found 55 diseases that correlated with the season of birth
April babies at highest risk of angina, November bronchitis and ADHD
Overall, the Columbia University study indicated people born in May had the lowest disease risk, and those born in October the highest.
'Lifetime disease risk is affected by birth month,' the researchers wrote in in the Journal of American Medical Informatics Association.
'Seasonally dependent early developmental mechanisms may play a role in increasing lifetime risk of disease. '
'This data could help scientists uncover new disease risk factors,' said author Nicholas Tatonetti.
The researchers now plan to replicate their study with data from several other locations in the U.S. and abroad to see how results vary with the change of seasons and environmental factors in those places.
By identifying what's causing disease disparities by birth month, the researchers hope to figure out how they might close the gap.
Earlier research on individual diseases such as ADHD and asthma suggested a connection between birth season and incidence, but no large-scale studies had been undertaken.
Researchers examined New York City medical databases and found 55 diseases that correlated with the season of birth. This data visualization maps the statistical relationship between birth month and disease incidence in the electronic records of 1.7 million New York City patients.
The researchers also uncovered 16 new associations, including nine types of heart disease, the leading cause of death in the United States.
The researchers performed statistical tests to check that the 55 diseases for which they found associations did not arise by chance.
'It's important not to get overly nervous about these results because even though we found significant associations the overall disease risk is not that great,' notes Dr. Tatonetti. 'The risk related to birth month is relatively minor when compared to more influential variables like diet and exercise.'
The new data are consistent with previous research on individual diseases.
For example, the study authors found that asthma risk is greatest for July and October babies.
An earlier Danish study on the disease found that the peak risk was in the months (May and August) when Denmark's sunlight levels are similar to New York's in the July and October period.
For ADHD, the Columbia data suggest that around one in 675 occurrences could relate to being born in New York in November.
This result matches a Swedish study showing peak rates of ADHD in November babies.
The researchers also found a relationship between birth month and nine types of heart disease, with people born in March facing the highest risk for atrial fibrillation, congestive heart failure, and mitral valve disorder.
One in 40 atrial fibrillation cases may relate to seasonal effects for a March birth.
A previous study using Austrian and Danish patient records found that those born in months with higher heart disease rates -March through June -had shorter life spans.
'Faster computers and electronic health records are accelerating the pace of discovery,' said the study's lead author, Mary Regina Boland, a graduate student at Columbia.
'We are working to help doctors solve important clinical problems using this new wealth of data.'
