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Amani Research institute is a research institute located at Amani, in the Muheza District, on the Western Usambara Mountains of the northeastern region in present-day Tanzania. The mountains form part of the Eastern Arc Mountains, which stretch from Kenya through Tanzania, and are covered by tropical cloud forests that have endured a long period of unique evolutionary endemism.
Founded during colonial rule in German East Africa in 1902 as research institute, it gained a strong reputation for botanical and agricultural research, as well as for the investigation of tropical diseases and the production of medical products. After World War I, work at Amani was continued under British administration and later became a station of the National Institute for Medical Research (NIMR) of Tanzania.

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